Secondary hemophagocytic lymphohistiocytosis due to miliary tuberculosis: diagnostic challenge and therapeutic dilemma
DOI:
https://doi.org/10.32818/reccmi.a9n2a10Keywords:
hemophagocytic lymphohistiocytosis, pancytopenia, miliary tuberculosis, immune reconstitution inflammatory syndromeAbstract
Hemophagocytic syndrome or lymphohistiocytosis hemophagocytic is a severe syndrome of excessive immune activation. We present a case study of hemophagocytic lymphohistiocytosis with severe pancytopenia due to miliary tuberculosis in a 62-year-old woman. During the antituberculosis treatment, the patient experienced radiological worsening, which was likely due to an immune reconstitution inflammatory syndrome. This case highlights on the importance of considering tuberculosis as a potential trigger and, if suspected, antituberculosis therapy should be initiated early, even in the absence of a definitive diagnosis.
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Copyright (c) 2024 Marina Delgado-Gómez , Marina Muñoz-Hernández, Miguel Ángel Sáez-García, Ana Gómez-Berrocal
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