Gastric perforation secondary to invasive candidiasis

Authors

  • Andrea Afonso-Díaz Internal Medicine Department, Hospital Universitario Nuestra Señora de la Candelaria, Santa Cruz de Tenerife, Spain https://orcid.org/0000-0001-7612-1165
  • Miguel Gutiérrez-de León Family and Community Medicine Department, Hospital Universitario Nuestra Señora de la Candelaria, Santa Cruz de Tenerife, Spain https://orcid.org/0009-0009-7041-8780
  • Xavier Esquirol-Puig Intensive Medicien Department, Hospital General de Granollers, Granollers, Barcelona, Spain https://orcid.org/0009-0008-1711-9442

DOI:

https://doi.org/10.32818/reccmi.a8n1a7

Keywords:

candida albicans, gastric perforation, invasive candidiasis

Abstract

We present the case of a patient who suffered perforation due to gastric wall necrosis due to invasive candida albicans with secondary abdominal septic shock. This is an immunocompetent middle-aged patient with underlying gastrointestinal pathology. Empirical broad-spectrum antibiotic therapy and vasoactive support were started in the ICU, requiring diagnostic-therapeutic laparotomy. In the samples collected and analyzed by Pathological Anatomy and microbiology, the presence of this fungus is evident. During admission, risk factors for said infectious entity were ruled out and the patient finally evolved favorably. There are different mechanisms by which Candida spp. it can become an opportunistic germ. These depend mainly on the conditioning factors and comorbidity of the host and on the mechanisms and intrinsic characteristics of the germ that increase its pathogenicity. Invasive gastric candidiasis is very rare and can present in a nodular or ulcerative form. Early diagnosis and specific treatment with antifungals provide a reduction in mortality. It is important to take this entity into account in patients with gastric perforation without a clear triggering cause and if there is a poor clinical evolution with antibiotic treatment.

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References

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Published

2023-04-30

How to Cite

1.
Afonso-Díaz A, Gutiérrez-de León M, Esquirol-Puig X. Gastric perforation secondary to invasive candidiasis. Rev Esp Casos Clin Med Intern [Internet]. 2023 Apr. 30 [cited 2024 Jul. 22];8(1):20-2. Available from: https://www.reccmi.com/RECCMI/article/view/805

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