Leukemia cutis. Not all edema is heart failure

Authors

  • María José González-Merodio Internal Medicine Service, Fundació Salut Empordà, Figueres (Girona), Spain.
  • Zulema González del Valle-González Internal Medicine Service, Fundació Salut Empordà, Figueres (Girona), Spain.
  • Angels Quera Anatomic Pathology Service, Fundació Salut Empordà, Figueres (Girona), Spain.
  • Catalina Seguí-Crespí Family and Community Medicine, Girona Teaching Unit, Fundació Salut Empordà, Figueres (Girona), Spain.

DOI:

https://doi.org/10.32818/reccmi.a7n2a12

Keywords:

leukemia cutis, chronic lymphocytic leukemia, acute myeloid leukemia, infiltration, edema

Abstract

Leukemia cutis is a very rare infiltration of leukemic cells into the skin. Its clinical presentation is very variable and usually, appears after peripheral blood involvement. It is most often associated with monocytic or myelomonocytic leukemias and is a sign of disseminated disease. It can be a marker of recurrence, conditioning a poor prognosis and a decrease in short- and long-term survival. Skin biopsy presents dermal perivascular/periadnexal infiltrate of small monotonous lymphocytes with typical chronic lymphocytic leukemia immunophenotype (CD20+, CD5+, CD23+, CD43+, CD10-, cyclin D1-). 

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References

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Published

2022-08-30

How to Cite

1.
González-Merodio MJ, González del Valle-González Z, Quera A, Seguí-Crespí C. Leukemia cutis. Not all edema is heart failure. Rev Esp Casos Clin Med Intern [Internet]. 2022 Aug. 30 [cited 2024 Nov. 21];7(2):34-7. Available from: https://www.reccmi.com/RECCMI/article/view/784