Systemic sarcoidosis with gastrointestinal and hepatic involvement

Authors

  • María Rodil-Riera Pneumology Department, Hospital Universitario Central de Asturias, Oviedo (Asturias), Spain.
  • Andrés Castaño-García Digestive Service, Hospital Universitario Central de Asturias, Oviedo (Asturias), Spain.
  • Pablo Carballal-García Faculty of Medicine, University of Oviedo, Oviedo (Asturias), Spain
  • Carmen Álvarez-Navascués Digestive Service, Hospital Universitario Central de Asturias, Oviedo (Asturias), Spain.
  • Ricardo Antonio Gómez-de la Torre Internal Medicine Department, Hospital Universitario Central de Asturias, Oviedo (Asturias), Spain.

DOI:

https://doi.org/10.32818/reccmi.a7n2a10

Keywords:

sarcoidosis, ascites, granuloma, hepatic involvement

Abstract

Sarcoidosis is a systemic granulomatous disease of uncertain aetiology. It is diagnosed when non-necrotising granulomas are found in the absence of other autoimmune or infectious processes or external agents. The incidence of gastrointestinal involvement is estimated at 0.1-1.6%, while liver involvement occurs in 50-65% of cases, and may be subclinical or discovered in the study of liver enzyme abnormalities.

We present the case of a 51-year-old man with postprandial satiety, epigastric pain and refractory ascites in the context of sarcoidosis with gastrointestinal, and hepatic involvement. He was treated with prednisone and azathioprine with subsequent clinical stabilisation.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

References

Ghrenassia E, Mekinian A, Chapelon-Albric C, Levy P, Cosnes J, Sève P, et al. Digestive-tract sarcoidosis: French nationwide case-control study of 25 cases. Medicine (Baltimore). 2016; 95(29): e4279. Disponible en: http://dx.doi.org/10.1097/MD.0000000000004279 (último acceso: julio 2022).

Daldoul S, Triki W, El Jeri K, Zaouche A. Unusual presentation of a colonic sarcoidosis. Case Rep Med [Internet]. 2012; 2012: 169760. Disponible en: http://dx.doi.org/10.1155/2012/169760 (ultimo acceso: julio 2022).

Shah N, Mitra A. Gastrointestinal and hepatic sarcoidosis: A review article. Clin Liver Dis (Hoboken). 2021; 17(4): 301–7. Disponible en: http://dx.doi.org/10.1002/cld.1055 (último acceso: julio 2022).

Sedki M, Fonseca N, Santiago P, Diaz L, Garcia-Buitrago M, Mirsaeidi M, et al. Hepatic sarcoidosis: Natural history and management implications. Front Med (Lausanne). 2019; 6: 232. Disponible en: http://dx.doi.org/10.3389/fmed.2019.00232 (último acceso: julio 2022).

Brito-Zerón P, Bari K, Baughman RP, Ramos-Casals M. Sarcoidosis involving the gastrointestinal tract: Diagnostic and therapeutic management: Diagnostic and therapeutic management. Am J Gastroenterol [Internet]. 2019;114(8):1238–47. Disponible en: http://dx.doi.org/10.14309/ajg.0000000000000171 (último acceso: julio 2022).

Stemboroski L, Gaye B, Makary R, Monteiro C, Eid E. Isolated gastrointestinal sarcoidosis involving multiple gastrointestinal sites presenting as chronic diarrhea. ACG Case Rep J. 2016; 3(4): e198. Disponible en: http://dx.doi.org/10.14309/crj.2016.171 (último acceso: julio 2022).

Afshar K, BoydKing A, Sharma OP, Shigemitsu H. Gastric sarcoidosis and review of the literature. J Natl Med Assoc. 2010; 102(5): 419–22. Disponible en: http://dx.doi.org/10.1016/s0027-9684(15)30577-0 (último acceso: julio 2022).

Published

2022-08-30

How to Cite

1.
Rodil-Riera M, Castaño-García A, Carballal-García P, Álvarez-Navascués C, Gómez-de la Torre RA. Systemic sarcoidosis with gastrointestinal and hepatic involvement. Rev Esp Casos Clin Med Intern [Internet]. 2022 Aug. 30 [cited 2024 Jul. 22];7(2):27-30. Available from: https://www.reccmi.com/RECCMI/article/view/773