Pruritic digital lesions in a 45 year old woman
DOI:
https://doi.org/10.32818/reccmi.a7n2a4Keywords:
autoimmunity, celiac disease, gluten-free dietAbstract
Dermatitis herpetiformis is an uncommon autoimmune cutaneous eruption revealing gluten sensitivity. Affected patients typically develop intensely pruritic inflammatory papules and vesicles on the forearms, knees, scalp or buttocks. The vast majority of patients with dermatitis herpetiformis also associate a gluten-sensitive enteropathy (celiac disease), which is usually minimally symptomatic or asymptomatic.
This clinical report shows an atypical presentation of dermatitis herpetiformis, given that the primary cutaneous manifestation of our patient was a combination of painful purpuric macules, papules and petechiae on various unusual locations (fingertips and thumbs).
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Heinlin J, Knoppke B, Kohl E, Landthaler M, Karrer S. Dermatitis herpetiformis presenting as digital petechiae. Pediatr Dermatol. 2012 Mar-Apr; 29(2): 209-12. doi: https://doi.org/10.1111/j.1525-1470.2011.01401.x.
Hofmann SC, Nashan D, Bruckner-Tuderman L. Petechiae on the fingertips as presenting symptom of dermatitis herpetiformis Duhring. J Eur Acad Dermatol Venereol. 2009; 23(6): 732-3. doi: https://doi.org/10.1111/j.1468-3083.2009.03200.x.
Tu H, Parmentier L, Stieger M, Spanou Z, Horn M, Beltraminelli H et al. Acral purpura as leading clinical manifestation of dermatitis herpetiformis: report of two adult cases with a review of the literature. Dermatology. 2013; 227(1): 1-4. doi: https://doi.org/10.1159/000347108.
Borroni G, Biagi F, Ciocca O, Vassallo C, Carugno A, Cananzi R et al. IgA anti-epidermal transglutaminase autoantibodies: a sensible and sensitive marker for diagnosis of dermatitis herpetiformis in adult patients. J Eur Acad Dermatol Venereol. 2013; 27(7): 836-41. doi: https://doi.org/10.1111/j.1468-3083.2012.04586.x.
Caproni M, Antiga E, Melani L, Fabbri P; Italian Group for Cutaneous Immunopathology. Guidelines for the diagnosis and treatment of dermatitis herpetiformis. J Eur Acad Dermatol Venereol. 2009; 23(6): 633-8. doi: https://doi.org/10.1111/j.1468-3083.2009.03188.x.
Heading RC, Paterson WD, McClelland DB, Barnetson RS, Murray MS. Clinical response of dermatitis herpetiformis skin lesions to a gluten-free diet. Br J Dermatol. 1976; 94(5): 509-14. doi: https://doi.org/10.1111/j.1365-2133.1976.tb05138.x.
Salmi TT, Hervonen K, Kautiainen H, Collin P, Reunala T. Prevalence and incidence of dermatitis herpetiformis: a 40-year prospective study from Finland. Br J Dermatol. 2011; 165(2): 354-9. doi: https://doi.org/10.1111/j.1365-2133.2011.10385.x.
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