Atypical adrenal myelolipoma in patient with resistant hypertension

Authors

  • María Toledano Internal Medicine Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
  • Karen Encalada-Luna Internal Medicine Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
  • Solsireé Moreno Department of Anatomic Pathology, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
  • Enrique Ramón-Botella Radiodiagnosis Service, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
  • Ana Torres-Do Rego Internal Medicine Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
  • Elena Bello-Martínez Internal Medicine Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain.

DOI:

https://doi.org/10.32818/reccmi.a7n2a5

Keywords:

adrenocortical adenoma, resistant hypertension, myelolipoma, pheochromocytoma

Abstract

Adrenal myelolipoma is a slow-growing tumour, composed of fatty tissue and haematopoietic elements, typically non-secretory, although a low percentage is associated with endocrine pathology.
We present the case of a 35-year-old man who, during the study of resistant arterial hypertension, was diagnosed with a large adrenal incidentaloma with an image congruent with adrenal myelolipoma, whose analytical determinations were anodyne, suggesting a non-functioning adenoma. After surgical resection, the anatomopathological study of the mass revealed pheochromocytoma cells, which produce catecholamines and are responsible for the patient's high blood pressure resistance.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

References

Oliveira Caiafa R, Salvador Izquierdo R, Buñesch Villalba L, Sebastià Cerqueda MC, Nicolau Molina C. Manejo y diagnóstico del incidentaloma suprarrenal. Radiologia. 2011;53(6): 516-30. doi: https://doi.org/10.1016/j.rx.2011.06.006.

Pérez Martínez J, Llamas F, López Rubio E, Serrano A, Salinas Sánchez A, Ruiz Mondéjar R et al. Mielolipoma suprarrenal gigante: hipertensión, insuficiencia renal y rotura espontánea. Nefrologia. 2006; 26(1): 132-5.

Decmann Á, Perge P, Tóth M, Igaz P. Adrenal myelolipoma: a comprehensive review. Endocrine. 2018; 59(1): 7-15. doi: https://doi.org/10.1007/s12020-017-1473-4.

Guerrero MA, Schreinemakers JM, Vriens MR, Suh I, Hwang J, Shen WT et al. Clinical spectrum of pheochromocytoma. J Am Coll Surg. 2009; 209(6): 727-32. doi: https://doi.org/10.1016/j.jamcollsurg.2009.09.022.

Sutton MG, Sheps SG, Lie JT. Prevalence of clinically unsuspected pheochromocytoma. Review of a 50-year autopsy series. Mayo Clin Proc. 1981; 56(6): 354-60.

Beard CM, Sheps SG, Kurland LT, Carney JA, Lie JT. Occurrence of pheochromocytoma in Rochester, Minnesota, 1950 through 1979. Mayo Clin Proc. 1983; 58(12): 802-4.

Baguet JP, Hammer L, Mazzuco TL, Chabre O, Mallion JM, Sturm N et al. Circumstances of discovery of phaeochromocytoma: a retrospective study of 41 consecutive patients. Eur J Endocrinol. 2004; 150(5): 681-6. doi: https://doi.org/10.1530/eje.0.1500681.

Sawka AM, Jaeschke R, Singh RJ, Young WF Jr. A comparison of biochemical tests for pheochromocytoma: measurement of fractionated plasma metanephrines compared with the combination of 24-hour urinary metanephrines and catecholamines. J Clin Endocrinol Metab. 2003; 88(2): 553-8. doi: https://doi.org/10.1210/jc.2002-021251.

Aliasgari M, Ghadian A. Coincidence of angiomyolipoma and pheochromocytoma. Urol J. 2006; 3(1): 61-4. doi: https://doi.org/10.22037/uj.v3i1.217.

Published

2022-08-30

How to Cite

1.
Toledano M, Encalada-Luna K, Moreno S, Ramón-Botella E, Torres-Do Rego A, Bello-Martínez E. Atypical adrenal myelolipoma in patient with resistant hypertension. Rev Esp Casos Clin Med Intern [Internet]. 2022 Aug. 30 [cited 2024 Jul. 3];7(2):12-4. Available from: https://www.reccmi.com/RECCMI/article/view/734

Most read articles by the same author(s)