Lady Windermere syndrome

Authors

  • Lidia Romero-Calvo Servicio de Medicina Interna, Hospital Central de la Defensa Gómez Ulla, Madrid, Spain
  • María Dolores Herrero-Mendoza Servicio de Medicina Interna, Hospital Central de la Defensa Gómez Ulla, Madrid, Spain
  • Luisa Jiménez-Reyes Servicio de Medicina Interna, Hospital Central de la Defensa Gómez Ulla, Madrid, Spain
  • Laura Checa-Daimiel Servicio de Medicina Interna, Hospital Central de la Defensa Gómez Ulla, Madrid, Spain
  • Javier Álvarez-Granda Servicio de Medicina Interna, Hospital Central de la Defensa Gómez Ulla, Madrid, Spain

DOI:

https://doi.org/10.32818/reccmi.a7n1a7

Keywords:

Lady Windermere syndrome, bronchiectasis, Mycobacterium avium complex

Abstract

Lady Windermere syndrome was defined more than 20 years ago by Reich and Johnson who used this term to describe pulmonary infection by Mycobacterium avium complex (MAC) limited to the middle lobe and/or lingula. We present a case of a 95-year-old woman, with no history of known pulmonary disease, presenting with constitutional syndrome and chronic cough, diagnosed with MAC infection in these areas.

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References

Reich JM, Johnson RE. Mycobacterium avium complex pulmonary disease presenting as an isolated lingular or middle lobe pattern: The Lady Windermere syndrome. Chest. 1992; 101(6): 1605-9. https://doi.org/10.1378/chest.101.6.1605.

Prince DS, Peterson DD, Steiner RM, Gottlieb JE, Scott R, Israel HL et al. Infection with Mycobacterium avium complex in patients without predisposing conditions. N Engl J Med. 1989; 321(13): 863-8. https://doi.org/10.1056/NEJM198909283211304.

Dhillon SS, Watanakunakorn C. Lady Windermere syndrome: middle lobe bronchiectasis and Mycobacterium avium complex infection due to voluntary cough suppression. Clin Infect Dis. 2000; 30(3): 572-5. https://doi.org/10.1086/313726.

Simon P, Meurant F, Degives R. Le cas clinique du mois. Le syndrome de Lady Windermere [Lady Windermere syndrome]. Rev Med Liege. 2012; 67(1): 5-7.

Blanco-Conde S, Nebreda-Mayoral T, Labayru-Echeverría C, Brezmes-Valdivieso MF, López-Medrano R, Nogueira-González B. Lady Windermere syndrome in Castile and León. Enferm Infecc Microbiol Clin (Engl Ed). 2018; 36(10): 644-647. https://doi.org/10.1016/j.eimc.2017.12.008.

Published

2022-04-24

How to Cite

1.
Romero-Calvo L, Herrero-Mendoza MD, Jiménez-Reyes L, Checa-Daimiel L, Álvarez-Granda J. Lady Windermere syndrome. Rev Esp Casos Clin Med Intern [Internet]. 2022 Apr. 24 [cited 2025 Apr. 6];7(1):19-21. Available from: https://www.reccmi.com/RECCMI/article/view/717