Hemorrhage with the administration of insulin in a patient without a history of previous bleeding.
DOI:
https://doi.org/10.32818/reccmi.a6n3a4Keywords:
hemorrhage, hemophilia, paraneoplastic syndrome, diathesis, factor VIII.Abstract
We report the case of a 69-years-old man who spontaneously presented a hemorrhagic diathesis, hematomas, and small hemorrhages at insulin puncture sites, during his stay in the Internal Medicine department. A prolonged activated partial thromboplastin time was observed with the following diagnosis of an acquired type A hemophilia, with a severe inhibition of factor VIII as a paraneoplastic effect of a primary bladder tumor.
Acquired hemophilia is a rare disease with a predisposition for males. Usually, it is diagnosed with a certain delay since the main trigger is a hemorrhage in patients without previous history and with a prolonged TTPa.
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Copyright (c) 2021 Guillem Guix, Juan J. López-Núñez, Marc Sorigué, Cristina Tural
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