Fulminant hepatitis in a patient with primary amyloidosis with a complete hematological response
DOI:
https://doi.org/10.32818/reccmi.a7n1a5Keywords:
immunoglobulin light-chain amyloidosis, amyloidosis, liver failure, nephrotic syndromeAbstract
Primary amyloidosis is a systemic disease that results from abnormal kappa or lambda protein misfolding. The prognosis is poor, and the treatment includes chemotherapy. Hepatic disorders related to primary amyloidosis are found in at least 70% of autopsies. They have a bad prognosis factor, but their clinical manifestations are rare.
We report a patient aged 41 with an initial diagnosis of nephrotic syndrome. Renal biopsy showed amyloid deposition. The treatment included quimiotherapy, reaching a complete hematological response. Even though the patient developed a hepatic failure dying.
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Copyright (c) 2022 Ileana Gefaell-Larrondo, David Roldán-Cortés, Juan Churruca-Sarasqueta, Ángel Torralba-Morón
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