DRESS syndrome in a patient treated with sulfasalazine and amoxicillin-clavulanic acid

Authors

  • Rita Nogueiras-Álvarez Servicio de Farmacología Clínica. Hospital Universitario Marqués de Valdecilla. Santander. Cantabria. España
  • Aurora Gutiérrez-González Servicio de Alergología. Hospital El Bierzo. Ponferrada. León. España
  • Estefanía Alejandra Montenegro-Echeverría Servicio de Alergología. Hospital Universitario Marqués de Valdecilla. Santander. Cantabria. España
  • Ana María Arnáiz-García Servicio de Medicina Interna. Hospital Universitario Marqués de Valdecilla. Santander. Cantabria. España

DOI:

https://doi.org/10.32818/reccmi.a5n3a11

Keywords:

dress syndrome, drug hypersensitivity syndrome, drug reaction, clinical pharmacology, allergology.

Abstract

DRESS syndrome (Drug Rash with Eosinophilia and Systemic Symptoms) is a drug-induced hypersensitivity syndrome that occurs between 2-6 weeks after the first taking of the responsible drug. We describe the case of a 57-year-old man who was admitted to our hospital due to a respiratory infection and a skin rash that was placed in the context of a DRESS syndrome. The cutaneous manifestations worsened after the intake of amoxicillin during concomitant treatment with sulfasalazine. When DRESS syndrome is suspected, withdrawal of the responsible drugs is crucial to avoid a possible fatal outcome.

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Published

2020-12-31

How to Cite

1.
Nogueiras-Álvarez R, Gutiérrez-González A, Montenegro-Echeverría EA, Arnáiz-García AM. DRESS syndrome in a patient treated with sulfasalazine and amoxicillin-clavulanic acid. Rev Esp Casos Clin Med Intern [Internet]. 2020 Dec. 31 [cited 2024 Jul. 22];5(3):129-32. Available from: https://www.reccmi.com/RECCMI/article/view/562

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