Late Systemic Lupus Erythematosus associated with Sjögren's syndrome

Authors

  • Sara Carrascosa-García Servicio de Medicina Interna. Consorcio Hospital General Universitario Valencia. Valencia. España
  • Miguel Ángel Moruno-Benita Servicio de Cardiología. Consorcio Hospital General Universitario Valencia. Valencia. España
  • Álvaro García-Campos Servicio de Medicina Interna. Consorcio Hospital General Universitario Valencia. Valencia. España

DOI:

https://doi.org/10.32818/reccmi.a5n3a3

Keywords:

renal failure, systemic lupus erythematosus, sjögren syndrome, overlap syndrome, cytomegalovirus infection.

Abstract

We report the case of an elderly woman, with a previous diagnosis of Sjögren´s Syndrome with renal failure and haema- temesis. During admission, she presented infectious complications (diarrhea), with detection of cytomegalovirus viremia and subsequent improvement after antibiotic and antiviral therapy. The final diagnosis was an acute kidney injury due to a prerenal component because of low water intake and anaemia, postrenal component as a result of morphological changes, and intrinsic renal component on account of suspected lupus nephropathy (because of pathological urinary sediment). The suspected diagnosis was late-onset Systemic Lupus Erythematosus and Overlap Syndrome. Furthermore, underlying gastric neoplasia was suspected.

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References

Lockshin MD, Levine AB, Erkan D. Patients with overlap autoimmune disease differ from those with 'pure' disease. Lupus Sci Med. 2015; 2(1): e000084. doi: https://doi.org/10.1136/lupus-2015-000084.

Zufferey P, Meyer OC, Bourgeois P, Vayssairat M, Kahn MF. Primary systemic Sjögren syndrome (SS) preceding systemic lupus erythematosus: a retros- pective study of 4 cases in a cohort of 55 SS patients. Lupus. 1995; 4(1): 23-7. doi: https://doi.org/10.1177/096120339500400106.

Iaccarino L, Gatto M, Bettio S, Caso F, Rampudda M, Zen M, et al. Overlap connective tissue disease syndromes. Autoimmun Rev. 2013; 12(3): 363-73. doi: https://doi.org/10.1016/j.autrev.2012.06.004.

Manoussakis MN, Georgopoulou C, Zintzaras E, Spyropoulou M, Stavro- poulou A, Skopouli FN, et al. Sjögren's syndrome associated with systemic lupus erythematosus: clinical and laboratory profiles and comparison with primary Sjögren's syndrome. Arthritis Rheum. 2004; 50(3): 882-91. doi: https://doi.org/10.1002/art.20093.

Bertsias G, Cervera R, Boumpas DT. Systemic lupus erythematosus: pathogenesis and clinical features. In: Bijlsma J (ed). EULAR textbook on rheumatic diseases, London: BMJ Group, 2012, 476–505.

García-González M, Rodríguez-Lozano B, Bustabad S, Ferraz-Amaro I. Undif- ferentiated connective tissue disease: predictors of evolution into definite disease. Clin Exp Rheumatol. 2017 Sep-Oct;35(5):739-745.

Alonso MD, Martinez-Vazquez F, de Teran TD, Miranda-Filloy JA, Dierssen T, Blan- co R, et al. Late-onset systemic lupus erythematosus in Northwestern Spain: differences with early-onset systemic lupus erythematosus and literature review. Lupus. 2012; 21(10): 1135-1148. doi: https://doi.org/10.1177/0961203312450087.

Ko JH, Peck KR, Lee WJ, Lee JY, Cho SY, Ha YE, et al. Clinical presentation and risk factors for cytomegalovirus colitis in immunocompetent adult patients. Clin Infect Dis. 2015; 60(6): e20-26. doi: https://doi.org/10.1093/cid/ciu969.

Published

2020-12-31

How to Cite

1.
Carrascosa-García S, Moruno-Benita M Ángel, García-Campos Álvaro. Late Systemic Lupus Erythematosus associated with Sjögren’s syndrome. Rev Esp Casos Clin Med Intern [Internet]. 2020 Dec. 31 [cited 2024 Jul. 3];5(3):109-11. Available from: https://www.reccmi.com/RECCMI/article/view/557