Thrombocytopenic purpura secondary to COVID-19
DOI:
https://doi.org/10.32818/reccmi.a5n2a15Keywords:
purpura, thrombocytopenia, SARS-CoV-2.Abstract
Patient with purpuric lesions and severe platelet disease of 2.0 x 109/L. About respiratory symptoms he only referred dyspnea; on clinical ultrasound, we found B lines in several lung fields suggestive of bilateral pneumonic condensation, confirmed radiographically. SARS-CoV-2 PCR test was positive. The analytical results allowed us to conclude that it was immune thrombocytopenic purpura (ITP) due to that virus.
Treatment with hydroxychloroquine + lopinavir/ritonavir was initiated, also, methylprednisolone and immunoglobulin. The lesions remitted, the dyspnea disappeared and platelets increased. Subsequently, he required treatment with eltrombopag, which normalized platelet count.
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W. Guan, Z. Ni, Yu Hu, W. Liang, C. Ou, J, et all. Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med 2020; 382: 1708-20. doi: https://doi.org/10.1056/NEJMoa2002032.
Abrar-Ahmad Z, Lorenzo- Villalba N, Hassler P, Andrés E. Immune Thrombocytopenic Purpura in a Patient with Covid-19. N engl j med. doi: https://doi.org/10.1056/NEJMc2010472.
Mo Yang, Margaret HL Ng & Chi Kong Li (2005) Thrombocytopenia in patients with severe acute respiratory syndrome (review). Hematology, 10:2, 101-105, doi: https://doi.org/10.1080/10245330400026170.
Tang N, Li D, Wang X, Sun Z. Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia. J Thromb Haemost. 2020; 18: 844–847. doi: https://doi.org/10.1111/jth.14768.
Lillicrap D. Disseminated intravascular coagulation in patients with 2019- nCoV pneumonia. J Thromb Haemost. 2020; 18: 786–787. doi: https://doi.org/10.1111/jth.14781.
Amgalan A, Othman M. Exploring possible mechanisms for COVID-19 induced thrombocytopenia: Unanswered questions. Department of Biomedical and Molecular Sciences School of Medicine, Queen's University, Canada. doi: https://doi.org/10.1111/JTH.14832.
Panyang Xu, Qi Zhou, Jiancheno Xu. Mechanism of thrombocytopenia in COVID-19 patients. Ann Hematol 2020 Apr 15: 1-4. doi: https://doi.org/10.1007/s00277-020-04019-0
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Copyright (c) 2020 María José Macías-Reyes; Olga Ramón-Planell; Cristina Baca-Cano, Marta Cucurell-Palomas, María José Martínez-Gil
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