Febrile neutropenia

Authors

  • María Mar Cutillas-Pérez Servicio de Medicina Interna, Hospital Universitario Morales Meseguer, Murcia, Spain
  • Cristina Macía-Rodríguez Servicio de Medicina Interna, Hospital POVISA, Vigo (Pontevedra), España
  • Lucía Santomé-Couto Servicio de Oncología, Hospital POVISA, Vigo (Pontevedra), Spain
  • Javier de-la-Fuente-Aguado Servicio de Medicina Interna, Hospital POVISA, Vigo (Pontevedra), Spain

DOI:

https://doi.org/10.32818/reccmi.a5n1a15

Keywords:

febrile neutropenia, MASCC, Talcott, CISNE, outpatient treatment.

Abstract

Most chemotherapy treatments have a negative effect in myelopoiesis and the integrity of gastrointestinal mucous membranes, increasing the risk of invasive translocation infections of bacteria and/or fungi. Neutropenic fever is a serious complication; its mortality rate varies from 11 % to 50 % in the case of severe sepsis or septic shock. It is essential to recognize this early and start empirical antibacterial therapy immediately. In patients with good prognosis criteria, outpatient treatment is an option to consider.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

References

Taplitz RA, Kennedy EB, Bow EJ, Crews J, Gleason C, Hawley DK, et al. Outpatient management of fever and neutropenia in adults treated for malignancy: American Society of Clinical Oncology and Infectious Diseases Society of America Clinical Practice Guideline Update. J Clin Oncol. 2018 May 10; 36(14): 1443-1453. https://doi.org/10.1200/JCO.2017.77.6211.

Fonseca PJ, Carmona-Bayonas A, García IM, Marcos R, Castañón E, Antonio M, et al. A nomogram for predicting complications in patients with solid tumours and seemingly stable febrile neutropenia. Br J Cancer. 2016 May 24; 114(11): 1191-1198. https://doi.org/10.1038/bjc.2016.118.

Taplitz RA, Kennedy EB, Bow EJ, Crews J, Gleason C, Hawley DK, et al. Antimicrobial prophylaxis for adult patients with cancer-related immunosuppression: ASCO and IDSA Clinical Practice Guideline Update. J Clin Oncol. 2018 Oct 20; 36(30): 3043-3054. https://doi.org/10.1200/JCO.18.00374.

Freifeld AG, Bow EJ, Sepkowitz KA, Boeckh MJ, Ito JI, Mullen CA, et al. Infectious Diseases Society of America. Clinical practice guideline for the use of antimicrobial agents in neutropenic patients with cancer: 2010 update by the Infectious Diseases Society of America. Clin Infect Dis. 2011 Feb 15; 52(4): e56-93. https://doi.org/10.1093/cid/cir073.

Baden LR, Swaminathan S, Angarone M, Blouin G, Camins BC, Casper C, et al. prevention and treatment of cancer-related infections, Version 2.2016, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2016 Jul; 14(7): 882-913. https://doi.org/10.6004/jnccn.2016.0093.

Published

2020-04-30

How to Cite

1.
Cutillas-Pérez MM, Macía-Rodríguez C, Santomé-Couto L, de-la-Fuente-Aguado J. Febrile neutropenia. Rev Esp Casos Clin Med Intern [Internet]. 2020 Apr. 30 [cited 2024 Jul. 22];5(1):42-4. Available from: https://www.reccmi.com/RECCMI/article/view/530