Management of infections in pregnant patients

Authors

  • María Ángeles Requena-Calleja Servicio de Medicina Interna, Hospital Universitario Miguel Servet, Zaragoza, Spain
  • Javier Moreno-Díaz Servicio de Medicina Interna, Hospital Real Nuestra Señora de Gracia, Zaragoza, Spain

DOI:

https://doi.org/10.32818/reccmi.a5n1a18

Keywords:

pregnancy, urinary tract infection, teratogens, antibiotics.

Abstract

During pregnancy, there are physiological changes that produce changes in the pharmacokinetics of the different antimicrobials, in addition to the toxic effects they may have on the embryo and the fetus. Most antibiotics pass the blood-placental barrier and there is a limitation when conducting clinical trials in pregnancy to assess the efficacy of drugs or others. We present different clinical situations during pregnancy and the best antibiotic treatment options for each moment.

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References

Vallano A, Arnau JM. Antimicrobianos y embarazo. Enferm Infecc Microbiol Clin. 2009; 27(9): 536-542. https://doi.org/10.1016/j.eimc.2009.09.001.

Kenyon S, Pike K, Jones DR, Brocklehurst P, Marlow N, Salt A, et al. Childhood outcomes after prescription of antibiotics to pregnant women with spontaneous preterm labour: 7-year follow-up of the ORACLE II trial. Lancet. 2008; 372(9646): 1319-1327. https://doi.org/10.1016/S0140- 6736(08)61203-9.

Urbina O, Ferrández O, Salas E, Grau S. Seguridad de nitrofurantoína en el embarazo. Enferm Infecc Microbiol Clin. 2010 Jun-Jul; 28(6): 403. https://doi.org/10.1016/j.eimc.2009.12.016.

Published

2020-04-30

How to Cite

1.
Requena-Calleja M Ángeles, Moreno-Díaz J. Management of infections in pregnant patients. Rev Esp Casos Clin Med Intern [Internet]. 2020 Apr. 30 [cited 2024 Dec. 4];5(1):53-4. Available from: https://www.reccmi.com/RECCMI/article/view/527