Muscle weakness and polypharmacy

Authors

  • Ángela Botella-Zaragoza Servicio de Medicina Interna, Hospital General Universitario de Elche, Elche (Alicante), Spain
  • Joan Sanchis-Sanchis Servicio de Medicina Interna, Hospital General Universitario de Elche, Elche (Alicante), Spain
  • Cristina Bas-Reina Servicio de Medicina Interna, Hospital General Universitario de Elche, Elche (Alicante), Spain
  • María Andreo-Galera Servicio de Medicina Interna, Hospital General Universitario de Elche, Elche (Alicante), Spain
  • Antonia Mora-Rufete Servicio de Medicina Interna, Hospital General Universitario de Elche, Elche (Alicante), Spain

DOI:

https://doi.org/10.32818/reccmi.a5s1a14

Keywords:

pluripathology, myositis, hydroxymethylglutaryl-CoA reductase inhibitors, autoantibodies.

Abstract

A case report of a pluripatological 71-years-old man is presented. The patient had muscle weakness and muscle enzymes elevation (liver cytolysis, aldolase, LDH and CK), that was compatible with a proximal myopathy of subacute onset. We carried out differential diagnosis based on clinical findings, laboratory tests, presence of autoantibodies, electromyography and imaging tests. He was diagnosed of statin-associated autoimmune myopathy.

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References

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Mammen AL. Statin-associated autoimmune myopathy. N Engl J Med. 2016; 374(7): 664-669. doi: https://doi.org/10.1056/NEJMra1515161.

Nazir S, Lohani S, Tachamo N, Poudel D, Donato A. Statin-associated autoimmune myopathy: a systematic review of 100 cases. J Clin Rheumatol. 2017; 23(3): 149-154. doi: https://doi.org/10.1097/RHU.0000000000000497.

Pinal-Fernández I, Casal-Domínguez M, Mammen AL. Immune-mediated necrotizing myopathy. Curr Rheumatol Rep. 2018; 20(4): 21. doi: https://doi.org/10.1007/s11926-018-0732-6.

Published

2020-03-31

How to Cite

1.
Botella-Zaragoza Ángela, Sanchis-Sanchis J, Bas-Reina C, Andreo-Galera M, Mora-Rufete A. Muscle weakness and polypharmacy. Rev Esp Casos Clin Med Intern [Internet]. 2020 Mar. 31 [cited 2024 Jul. 3];5:37-8. Available from: https://www.reccmi.com/RECCMI/article/view/521

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