The dark side of amiodarone

Authors

  • María Amparo Vicente Altabás Servicio de Medicina Interna. Hospital Universitario Miguel Servet. Zaragoza. España
  • Lucia Martinez Barredo Servicio de Medicina Interna. Hospital Universitario Miguel Servet. Zaragoza. España
  • Luis Ignacio Fumanal Idocin Servicio de Medicina Interna. Hospital Universitario Miguel Servet. Zaragoza. España
  • Anyuli Gracia Gutierrez Servicio de Medicina Interna. Hospital General de la Defensa. Zaragoza. España

DOI:

https://doi.org/10.32818/reccmi.a5n2a2

Keywords:

amiodarone, adverse drug reaction, lung disease.

Abstract

Amiodarone pulmonary toxicity is a rare but serious entity. Its diagnosis is difficult because the clinic is nonspecific and the need to rule out other processes that simulate this pathology. A high degree of suspicion is important, to obtain an early diagnosis and early treatment, avoiding its progression to pulmonary fibrosis. We present a case that illustrates the diagnostic difficulty and the good clinical and radiological evolution after the withdrawal of amiodarone.

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References

- Papiris SA, Triantafillidou C, Kolilekas K, Markoulaki D, Manali ED. Amiodarone: review of pulmonary effects and toxicity. Drug Saf. 2010; 33(7): 539-58. doi: https://doi.org/10.2165/11532320-000000000-00000.

- Sánchez S, Zamora E, Hoyos N, Naranjo A, L Nakeeb Z, Girón RM. Fibrosis pulmonar por amiodarona. Rev Patol Respir 2006; 9(2): 77-80. Accesible en: https://www.revistadepatologiarespiratoria.org/descargas/pr_9-2_77-80.pdf. Ultimo acceso 19.11.2019

- Bernal Morell E, Hernández Madrid A, Marín Marín I, Rodríguez Pena R, González Gordaliza M, Moro C. Nódulos pulmonares múltiples y amiodarona. KL-6 como nueva herramienta diagnóstica. Rev Esp Cardiol. 2005; 58(4): 447-9.

- Bahena López E, Bucio Reta E, Bahena López J. Toxicidad pulmonar por amiodarona. Rev Invest Med Sur Mex 2015;22(4):214-217. Accesible en: https://www.medigraphic.com/pdfs/medsur/ms-2015/ms154k.pdf. Último acceso 19.11.2019.

- Wolkove N, Baltzan M. Amiodarone pulmonary toxicity. Can Respir J. 2009; 16(2): 43-48. doi: https://doi.org/10.1155/2009/282540.

Published

2020-08-31

How to Cite

1.
Vicente Altabás MA, Martinez Barredo L, Fumanal Idocin LI, Gracia Gutierrez A. The dark side of amiodarone. Rev Esp Casos Clin Med Intern [Internet]. 2020 Aug. 31 [cited 2024 Dec. 22];5(2):59-61. Available from: https://www.reccmi.com/RECCMI/article/view/478