A long-lasting febrile syndrome
DOI:
https://doi.org/10.32818/reccmi.a5n1a10Keywords:
adult-onset Still’s disease, fever, ferritin, hemophagocytosis, rash, splenomegaly, hemophagocytic syndrome.Abstract
It is necessary to include the hemophagocytic syndrome within the differential diagnosis of intermediate-long febrile syndrome. This is a rare and life-threatening entity due to immune hyperactivation. It is characterized by sepsis-like manifestations and it shows hemaphagocytosis (ingestion of blood cells and their precursors by macrophages). It can be primary or secondary to some disease, such as an infection or a neoplasia, as more frequent entities, or to an autoimmune disease, such as the adult-onset Still’s disease, as it was in our case. The secondary entities must be searched for to start the targeted treatment. It is essential an early diagnosis of hemophagocytic syndrome due to its severity and the mortality resulting from a delay in treatment and to the low incidence.
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Copyright (c) 2020 Elizabeth Lorenzo-Hernández, Fernando Salgado-Ordóñez, Iván Pérez-de-Pedro, Gloria Millán-García, Ricardo Gómez-Huelgas
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