Toxic drug epidermal necrolysis associated with nevirapine treatment: a case report

Authors

  • Reinaldo Luis Menéndez-Capote Instituto de Medicina Tropical Pedro Kouri, La Habana, Cuba
  • Hilario Olo-Olo Policlínico Virgen de Guadalupe, Mongomo, Equatorial Guinea
  • Paulina Obono-Engang Policlínico Virgen de Guadalupe, Mongomo, Equatorial Guinea
  • María de los Ángeles Chappotten-Delahanty Hospital Clínico Quirúrgico Joaquín Albarrán, La Habana, Cuba

DOI:

https://doi.org/10.32818/reccmi.a4n3a3

Keywords:

necrolysis, Stevens-Johnson syndrome, overlap syndrome

Abstract

Stevens-Johnson syndrome together with toxic epidermal necrolysis is part of a spectrum with different degrees of involvement in mucous membranes and skin, whose severity can cause death. The purpose of this report is to show the presence of this entity, which has increased its incidence, and in a group without experience in the management of these cases. A 22-year-old female patient with a history of human im- munodeficiency virus infection and of having started treatment with nevirapine; antiretroviral drug reverse transcriptase inhibitor, linked to the treatment of this disease. It is admitted due to severe cutaneous and mucous lesions; the treatment was conservative and, although slow, the patient evolved satisfactorily. The early start of the support measures, together with the immediate suspension of the drug contribute to the good evolutionary prognosis of the disease.

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Published

2019-12-31

How to Cite

1.
Menéndez-Capote RL, Olo-Olo H, Obono-Engang P, Chappotten-Delahanty M de los Ángeles. Toxic drug epidermal necrolysis associated with nevirapine treatment: a case report. Rev Esp Casos Clin Med Intern [Internet]. 2019 Dec. 31 [cited 2024 Dec. 22];4(3):107-10. Available from: https://www.reccmi.com/RECCMI/article/view/433

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