Lymphadenopathy related to IgG4 disease
DOI:
https://doi.org/10.32818/reccmi.a4n1a10Keywords:
lymphadenopathy, immunoglobulin IgG4, IgG4-related disease.Abstract
We present the case of a 49 year old man without previous diseases but toxic habits, who consulted to our Inter- nal Medicine Outpatient department due to the presence of mild fever and painfull axillar lymphadenopathies lasting for 7 months, with no other accompanying symptoms. Image tests (echography and body-scan) con- firmed the presence of multiple pathologic size axillary and inguinal lymphadenopathies, being transferred to surgery to proceed with lymphadenectomy. Anatomopathological lymphadenopathy study showed plasmatic cells with predominance of IgG4, with a IgG4/IgG ratio > 0.4. Analytic study was unremarkable, except for a mild IgG4 elevated value. Corticosteroid therapy is started, achieving complete resolution.
Downloads
Metrics
References
Ardila-Suárez O, Abril A, Gómez-Puerta JA. IgG4-related disease: a concise review of the current literature. Reumatol Clin. 2017 May-Jun; 13(3): 160-166. doi: https://doi.org/10.1016/j.reuma.2016.05.009.
Carrillo-Esper R, Echervarría Vargas JA. Enfermedad relacionada con IgG4. Med Int Mex. 2013; 29(1): 53-61.
Erlij D, Ramos D, Montaña J, Kusnir P, Correa G, Neira O. IgG4-related disease, the new "great mimicker": report of one case. Rev Med Chil. 2014 May; 142(5): 646-650. doi: https://doi.org/10.4067/S0034-98872014000500014.
Wick MR, O'Malley DP. Lymphadenopathy associated with IgG4-related disease: diagnosis & differential diagnosis. Semin Diagn Pathol. 2018 Jan; 35(1): 61-66. doi: https://doi.org/10.1053/j.semdp.2017.11.006.
Deshpande V, Zen Y, Chan JK, Yi EE, Sato Y, Yoshino T, et al. Consensus statement on the pathology of IgG4-related disease. Mod Pathol. 2012 Sep; 25(9): 1181-1192. doi: https://doi.org/10.1038/modpathol.2012.72.
Pieringer H, Parzer I, Wöhrer A, Reis P, Oppl B, Zwerina J. IgG4-related disease: an orphan disease with many faces. Orphanet J Rare Dis. 2014 Jul 16; 9: 110. doi: https://doi.org/10.1186/s13023-014-0110-z.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2019 Sara Pérez-Moyano, Alberto Benavente-Fernández, Beatriz Rueda-Villafranca
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Permite compartir, copiar y redistribuir el material en cualquier medio o formato, bajo los siguientes términos:
Reconocimiento: debe otorgar el crédito correspondiente, proporcionar un enlace a la licencia e indicar si se realizaron cambios. Puede hacerlo de cualquier manera razonable, pero no de ninguna manera que sugiera que el licenciante lo respalda a usted o su uso.
No comercial: no puede utilizar el material con fines comerciales.
No Derivados: si remezcla, transforma o construye sobre el material, no puede distribuir el material modificado.
Sin restricciones adicionales: no puede aplicar términos legales o medidas tecnológicas que restrinjan legalmente a otros de hacer cualquier cosa que permita la licencia.