Ni tipo 1 ni tipo 2: una diabetes de perfil infrecuente con base autoinmunitaria
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https://doi.org/10.32818/reccmi.a4s1a6Keywords:
diabetes mellitus, autoinmune polyglandular syndrome , latent autoinmune diabetes in adultsAbstract
We present a 66-year-old patient with history of Graves-Basedow disease, who was admitted in charge of Internal Medicine with suspected debut of diabetes mellitus, being initially catalogued as type 2. The poor response to treatment with oral antidiabetics, requiring insulin therapy to achieve a proper glycemic control, along with the underlying pathology, raised the suspicion of latent autoimmune diabetes in adults. This was confirmed by the discovery of specific positive autoantibodies. The association between these two pathologies also makes it possible to classify the patient within a group of autoimmune endocrine disorders known as type 3 polyglandular syndrome.
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American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care. 2014 Jan;37 Suppl 1:S81-90. doi: https://doi.org/10.2337/dc14-S081.
Lutgens MW, Meijer M, Peeters B, Poulsen ML, Rutten MJ, Bots ML et al. Easily obtainable clinical features increase the diagnostic accuracy for latent autoimmune diabetes in adults: an evidence-based report. Prim Care Diabetes. 2008 Dec;2(4):207-11. doi: https://doi.org/10.1016/j.pcd.2008.08.003. Epub 2008 Sep 23.
Hernández M, Mauricio D. Latent autoimmune diabetes in adults: are we paying sufficient attention? Endocrinol Nutr. 2015 Jan;62(1):1-3. doi: https://doi.org/10.1016/j.endonu.2014.12.001.
Rodríguez FJ, Pérez RB, Martell JAO, Takane EO. Síndrome Poliglandular Autoinmune tipo III. Honduras Pediatrica. 1997;18(2): 44-46
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Copyright (c) 2019 Miguel Martín-Romero, Miriam Navarro-Rodríguez, José David Galián-Ramírez, Raquel Pérez-Luján, Antonia María Castillo-Navarro
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