Diabetes mellitus y obesidad: la importancia de realizar un abordaje integral de ambas entidades

Authors

  • Miguel Martín-Romero Servicio de Medicina Interna, Hospital Clínico Universitario Virgen de la Arrixaca, Murcia, Spain
  • Miriam Navarro-Rodríguez Servicio de Medicina Interna, Hospital Clínico Universitario Virgen de la Arrixaca, Murcia, Spain
  • José David Galián-Ramírez Servicio de Medicina Interna, Hospital Clínico Universitario Virgen de la Arrixaca, Murcia, Spain
  • Raquel Pérez-Luján Servicio de Medicina Interna, Hospital Clínico Universitario Virgen de la Arrixaca, Murcia, Spain
  • Antonia María Castillo-Navarro Servicio de Medicina Interna, Hospital Clínico Universitario Virgen de la Arrixaca, Murcia, Spain

DOI:

https://doi.org/10.32818/reccmi.a4s1a3

Keywords:

diabetes mellitus type 2 , obesity, GLP-1 receptor agonists , SGLT2 inhibitors

Abstract

We present a 63-year-old woman diagnosed with type 2 diabetes mellitus in 2007 and grade III obesity, in addition to gonarthrosis and sequelae of a traffic accident. She was unable to perform physical exercise due to gonarthrosis and the aftermath of the traffic accident. Progressive treatment with oral antidiabetic agents did not achieve optimal glycemic control after several years of follow-up. Neither there was an improvement in obesity despite following several diets prescribed by specialists. We offered her therapy with insulin but the patient rejected it systematically. Finally, the use of combined treatment with agonists of the GLP-1 receptor and SGLT-2 inhibitors allowed to achieve an adequate glycemic control for the first time. In the subsequent controls, HbA1c values of less than 7% were reached, in addition to a significant reduction in body weight, with good tolerance and without adverse effects.

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References

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Inzucchi SE, Bergenstal RM, Buse JB, Diamant M, Ferrannini E, Nauck M et al. American Diabetes Association (ADA); European Association for the Study of Diabetes (EASD). Management of hyperglycemia in type 2 diabetes: a patient-centered approach: position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care. 2012 Jun;35(6):1364-79. doi: https://doi.org/10.2337/dc12-0413. Epub 2012 Apr 19.

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Bennett WL, Maruthur NM, Singh S, Segal JB, Wilson LM, Chatterjee R et al. Comparative effectiveness and safety of medications for type 2 diabetes: an update including new drugs and 2-drug combinations. Ann Intern Med. 2011 May 3;154(9):602-13. doi: https://doi.org/10.7326/0003-4819-154-9-201105030-00336. Epub 2011 Mar 14.

Published

2019-01-31

How to Cite

1.
Martín-Romero M, Navarro-Rodríguez M, Galián-Ramírez JD, Pérez-Luján R, Castillo-Navarro AM. Diabetes mellitus y obesidad: la importancia de realizar un abordaje integral de ambas entidades. Rev Esp Casos Clin Med Intern [Internet]. 2019 Jan. 31 [cited 2024 Dec. 22];4:5-6. Available from: https://www.reccmi.com/RECCMI/article/view/343

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