Lithium poisoning. A case of multi-organ dysfunction

Authors

  • Helena Sofia Santos-Gonçalves Departamento de Medicina Interna, Hospital de Vila Real, Centro Hospitalar de Trás os Montes e Alto Douro, Vila Real, Portugal
  • Andre Terras Alexandre Departamento de Neumología, Hospital de Vila Real, Centro Hospitalar de Trás os Montes e Alto Douro, Vila Real, Portugal
  • Ana Filipa Rebelo Departamento de Medicina Interna, Hospital de Vila Real, Centro Hospitalar de Trás os Montes e Alto Douro, Vila Real, Portugal

DOI:

https://doi.org/10.32818/reccmi.a3n3a8

Keywords:

lithium, poisoning, hypothyroidism, chronic cardiomyopathy

Abstract

Lithium is a widely used drug which has a very narrow therapeutic range, because of its potential of toxicity. Lithium poisoning can affect vary organs, and have different pardons of presentation. We present a multi-organ lithium toxicity case in a patient under chronic treatment with lithium for bipolar disease.

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References

Altschul E, Dougherty R, Gaikwad R, Nguyen V, Schwimmer J, Merker E, et al. Lithium toxicity: a review of pathophysiology, treatment, and prognosis. Practical neurology. 2016 March: 42-45.

Gitlin M. Lithium side effects and toxicity: prevalence and management strategies. Int J Bipolar Disord. 2016; 4(1): 27.

Baird-Gunning J, Lea-Henry T, Hoegberg LCG, Gosselin S, Roberts DM. Lithium poisoning. J Intensive Care Med. 2017 May; 32(4): 249-263. doi: https://doi.org/10.1177/0885066616651582.

Kibirige D, Luzinda K, Ssekitoleko R. Spectrum of lithium induced thyroid abnormalities: a current perspective. Thyroid Res. 2013 Feb 7; 6(1): 3. doi: https://doi.org/10.1186/1756-6614-6-3.

Brady HR, Horgan JH. Lithium and the heart. Unanswered questions. Chest. 1988; 93(1): 166-169.

Aichhorn W, Huber R, Stuppaeck C, Whitworth AB. Cardiomyopathy after long-term treatment with lithium - more than a coincidence? J Psychopharmacol. 2006; 20(4): 589-591.

Anantha Narayanan M, Mahfood Haddad T, Bansal O, Baskaran J, Azzouz MS, Akinapelli A, et al. Acute cardiomyopathy precipitated by lithium: is there a direct toxic effect on cardiac myocytes? Am J Emerg Med. 2015 Sep; 33(9): 1330.e1-5. doi: https://doi.org/10.1016/j.ajem.2015.03.023.

Grais IM, Sowers JR. Thyroid and the heart. Am J Med. 2014 Aug; 127(8): 691-698. doi: https://doi.org/10.1016/j.amjmed.2014.03.009.

Published

2018-12-31

How to Cite

1.
Santos-Gonçalves HS, Alexandre AT, Rebelo AF. Lithium poisoning. A case of multi-organ dysfunction. Rev Esp Casos Clin Med Intern [Internet]. 2018 Dec. 31 [cited 2024 Jul. 22];3(3):125-6. Available from: https://www.reccmi.com/RECCMI/article/view/305

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