Post-fibrinolysis complication as embolic release of unknown intracavitary thrombus

Authors

  • Juncal Sánchez-Arguiano Servicio de Medicina Intensiva, Hospital Universitario Marqués de Valdecilla, Santander, Spain
  • Maite Arlabán-Carpintero Servicio de Medicina Intensiva, Hospital Universitario Marqués de Valdecilla, Santander, Spain
  • Enrique Chicote-Álvarez Servicio de Medicina Intensiva, Hospital Universitario Marqués de Valdecilla, Santander, Spain
  • María Ángeles Ballesteros-Sanz Servicio de Medicina Intensiva, Hospital Universitario Marqués de Valdecilla, Santander, Spain
  • Manuel Gayol-Fernández Atención Primaria, Servicio de Salud del Principado de Asturias, Spain

DOI:

https://doi.org/10.32818/reccmi.a3n3a2

Keywords:

mobile cardiac thrombus, thrombolysis, multiple ictus

Abstract

Fibrinolytic therapy is the mainstay of the treatment of acute ischemic stroke. New embolic strokes as a complication of fibrinolytic treatment are described in a few cases in literature. It is believed that it could be due to the disintegration of a preexisting intracardiac thrombus. We present the case of a 63-year-old patient admitted for ischemic stroke of the left middle cerebral artery who undergoes fibrinolysis, after that she suffered multiple infarctions in different vascular territories, as consequence of a release of fragments of an intraventricular not-know thrombus. Early neurological deterioration after thrombolysis, with association of clinical signs corresponding to another vascular territory (different from the initially affected one), we should think about this entity.

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References

Powers WJ, Derdeyn CP, Biller J, Coffey CS, Hoh BL, Jauch EC, et al. 2015 American Heart Association/American Stroke Association Focused Update of the 2013 guidelines for the early management of patients with acute ischemic stroke regarding endovascular treatment: a guideline for healthcare professionals from the American Heart Association/American Stroke Asso- ciation. Stroke. 2015; 46: 3020-3035. doi: https://doi.org/10.1161/STR.0000000000000074.

Powers WJ, Rabinstein AA, Ackerson T, Adeoye OM, Bambakidis NC, Becker K, et al. 2018 Guidelines for the early management of patients with acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2018 Mar; 49(3): e46-e110. doi: https://doi.org/10.1161/STR.0000000000000158.

Kamal H, Mowla A, Farooq S, Shirani P. Recurrent ischemic stroke can happen in stroke patients very early after intravenous thrombolysis. J Neurol Sci. 2015; 358: 496-497. doi: https://doi.org/10.1016/j.jns.2015.09.020.

Tanaka K, Ohara T, Ishigami A, Ikeda Y, Matsushige T, Satow T, et al. Fatal multiple systemic emboli after intravenous thrombolysis for cardioembolic stroke. J Stroke Cerebrovasc Dis. 2014 Feb; 23(2): 395-397. doi: https://doi.org/10.1016/j.jstrokecerebrovasdis.2013.03.007.

Yalcin-Cakmakli G, Akpinar E, Topcuoglu MA, Dalkara T. Right internal carotid artery occlusion during intravenous thrombolysis for left middle cerebral artery occlusion. J Stroke Cerebrovasc Dis. 2009 Jan; 18(1): 74-77. doi: https://doi.org/10.1016/j.jstrokecerebrovasdis.2008.08.007.

Oberreuter G, Silva N, Caba S, Morales M, Nieto E, Guevara C. Accidente cerebrovascular isquémico en pacientes con trombo intracavitario: experiencia con tratamientos distintos en fase aguda. Rev Med Chil. 2014 Sep; 142(9): 1200-1204. doi: https://doi.org/10.4067/S0034-98872014000900015.

Kobayashi M, Tanaka R, Yamashiro K, Ueno Y, Kato E, Miura S, et al. Preexisting mobile cardiac thrombus and the risk of early recurrent embolism after intravenous thrombolysis: a case report. J Stroke Cerebrovasc Dis. 2015 Jun; 24(6): e161-3. doi: https://doi.org/10.1016/j.jstrokecerebrovasdis.2015.03.001.

Safouris A, Kargiotis O, Magoufis G, Katsanos AH, Stamboulis E, Tsivgoulis G. Early neurological deterioration during alteplase infusion for acute ischemic stroke: an uncommon complication of intravenous thrombolysis. Neurologist. 2017 May; 22(3): 90-91. doi: https://doi.org/10.1097/NRL.0000000000000118.

Published

2018-12-31

How to Cite

1.
Sánchez-Arguiano J, Arlabán-Carpintero M, Chicote-Álvarez E, Ballesteros-Sanz M Ángeles, Gayol-Fernández M. Post-fibrinolysis complication as embolic release of unknown intracavitary thrombus. Rev Esp Casos Clin Med Intern [Internet]. 2018 Dec. 31 [cited 2024 Jul. 22];3(3):107-9. Available from: https://www.reccmi.com/RECCMI/article/view/299