Subcutaneous sarcoidosis in a patient with chronic hepatitis C virus infection

Authors

  • Marina Fayos Servicio de Medicina Interna, Hospital Universitario Marqués de Valdecilla-IDIVAL. Universidad de Cantabria, Santander, Spain
  • José M. Olmos-Martínez Servicio de Aparato Digestivo, Hospital Universitario Marqués de Valdecilla-IDIVAL. Universidad de Cantabria, Santander, Spain
  • Remigio Mazorra Servicio de Anatomía Patológica, Hospital Universitario Marqués de Valdecilla-IDIVAL. Universidad de Cantabria, Santander, Spain
  • José D. García-Palacios Servicio de Medicina Interna, Hospital Universitario Marqués de Valdecilla-IDIVAL. Universidad de Cantabria, Santander, Spain
  • José M. Olmos Servicio de Medicina Interna, Hospital Universitario Marqués de Valdecilla-IDIVAL. Universidad de Cantabria, Santander, Spain

DOI:

https://doi.org/10.32818/reccmi.a3n3a3

Keywords:

cutaneous sarcoidosis, hepatitis C virus infection, interferon, ribavirin, boceprevir

Abstract

Subcutaneous sarcoidosis or Darier-Roussy disease is a very rare variant of this disease. Sarcoidosis is a disease which still has uncertain etiology, although some cases have been described in patients with chronic hepatitis C virus (HCV) infection, especially after receiving treatment with interferon. We present the case of a patient with HCV infection who developed a subcutaneous sarcoidosis a few months after receiving treatment with Interferon, Rivabirine and Boceprevir. Although it could be a casual association, it would be advisable to study the possible role of HCV and treatment with IFN in the pathogenesis of this disease.

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References

Ungprasert P, Wetter DA, Crowson CS, Matteson EL. Epidemiology of cutaneous sarcoidosis, 1976-2013: a population-based study from Olmsted County, Minnesota. J Eur Acad Dermatol Venereol. 2016 Oct; 30(10): 1799- 1804. doi: https://doi.org/10.1111/jdv.13760.

Ando M, Miyazaki E, Hatano Y, Nishio S, Torigoe C, Yamasue M, et al. Subcutaneous sarcoidosis: a clinical analysis of nine patients. Clin Rheumatol. 2016 Sep; 35(9): 2277-2281. doi: https://doi.org/10.1007/s10067-016-3356-0.

Ramos-Casals M, Mañá J, Nardi N, Brito-Zeron P, Xaubet A, Sánchez-Tapias JM, et al. Sarcoidosis in patients with chronic hepatitis C virus infection: analysis of 68 cases. Medicine (Baltimore). 2005; 84: 69-80.

Bonnet F, Morlat P, Dubuc J, De Witt S, Bonarek M, Bernard N, et al. Sarcoidosis-associated hepatitis C virus infection. Dig Dis Sci. 2002; 47: 794-796.

Fallahi P, Ferri C, Ferrari SM, Corrado A, Sansonno D, Antonelli A. Cytokines and HCV-related disorders. Clin Dev Immunol. 2012; 2012: 468107. doi: https://doi.org/10.1155/2012/468107.

Rogers CJ, Romagosa R, Vincek V. Cutaneous sarcoidosis associated with pegylated interferon alfa and ribavirin therapy in a patient with chronic hepatitis C. J Am Acad Dermatol. 2004; 50: 649-650.

Blum L, Serfaty L, Wattiaux MJ, Picard O, Cabane J, Imbert JC. Nodules hypodermiques sarcoidosiques au cours d’une hepatite virale C traitee par interferon alpha 2b. Rev Med Interne. 1993; 14(Suppl 462): 1161.

Ramírez C, Faúndez C, Valdés MP, de la Fuente R, Carreño L. Sarcoidosis subcutánea como manifestación inicial de sarcoidosis sistémica. Piel (Barc). 2013; 28: 387-390. doi: https://doi.org/10.1016/j.piel.2013.01.015.

Published

2018-12-31

How to Cite

1.
Fayos M, Olmos-Martínez JM, Mazorra R, García-Palacios JD, Olmos JM. Subcutaneous sarcoidosis in a patient with chronic hepatitis C virus infection. Rev Esp Casos Clin Med Intern [Internet]. 2018 Dec. 31 [cited 2024 Nov. 24];3(3):110-2. Available from: https://www.reccmi.com/RECCMI/article/view/291

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