Weakness and metabolic acidosis: anamnesis is the answer.

Authors

  • Gustavo Alexis Lemus-Barrios Servicio de Medicina Interna. Universidad Tecnológica de Pereira. Colombia https://orcid.org/0000-0001-9509-8220
  • Julián Andrés Hoyos-Pulgarín Servicio de Medicina Interna. Universidad Tecnológica de Pereira. Colombia
  • Oscar Iván Gutiérrez-Sanjuán Servicio de Medicina Interna. Universidad Tecnológica de Pereira. Colombia
  • Jacklyn Cristina Guzmán-Montealegre Servicio de Medicina Interna. Universidad Tecnológica de Pereira. Colombia

DOI:

https://doi.org/10.32818/reccmi.a3n1a12

Keywords:

toluene toxicity, acid-base imbalance, renal tubular acidosis.

Abstract

Weakness secondary to the loss of muscle strength is a frequent reason for consultation in the emergency ser- vices and includes a wide spectrum of differential diagnoses. When accompanied by metabolic acidosis, electrolyte disturbances and a history of inhalant abuse, toluene toxicity should be suspected. We present the case of a young patient with abuse of inhalants who presented a toluene intoxication manifested by an arreflexic quadriparesis, associated with metabolic acidosis with elevated anion gap and severe hypokalemia. The diagnosis was made after performing a detailed anamnesis.

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References

Camara-Lemarroy CR, Rodríguez-Gutiérrez R, Monreal-Robles R, González- González JG. Acute toluene intoxication–clinical presentation, management and prognosis: a prospective observational study. BMC Emerg Med [Internet]. 2015 Aug 18; 15: 19.

Carlisle EJ, Donnelly SM, Vasuvattakul S, Kamel KS, Tobe S, Halperin ML. Glue-sniffing and distal renal tubular acidosis: sticking to the facts. J Am Soc Nephrol. 1991 Feb; 1(8): 1019-1027.

Assadi F. Diagnosis of hypokalemia: a problem solving approach to clinical cases. Iran J Kidney Dis. 2008 Jul; 2(3): 115-122.

Lin SH. A practical and pathophysiologic approach to hypokalemia. Hong Kong J Nephrol. 2008 Apr; 10(1): 14-26.

Dickson RP, Luks AM. Toluene toxicity as a cause of elevated anion gap metabolic acidosis. Respir Care. 2009 Aug; 54(8): 1115-1117.

Rastegar A. Use of the DeltaAG/DeltaHCO3-ratio in the diagnosis of mixed acid-base disorders. J Am Soc Nephrol. 2007 Sep; 18(9): 2429-2431.

Voss J-U, Roller M, Brinkmann E, Mangelsdorf I. Nephrotoxicity of organic solvents: biomarkers for early detection. Int Arch Occup Environ Health. 2005 Jul; 78(6): 475-485.

Published

2018-04-30

How to Cite

1.
Lemus-Barrios GA, Hoyos-Pulgarín JA, Gutiérrez-Sanjuán OI, Guzmán-Montealegre JC. Weakness and metabolic acidosis: anamnesis is the answer. Rev Esp Casos Clin Med Intern [Internet]. 2018 Apr. 30 [cited 2024 Nov. 15];3(1):34-6. Available from: https://www.reccmi.com/RECCMI/article/view/262

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