Overlap myositis, a diagnostic challenge where antibody determination enabled diagnostic confirmation

Authors

  • Paula Luque-Linero Servicio de Medicina Interna, Hospital Universitario Virgen Macarena, Sevilla, España https://orcid.org/0000-0001-5150-4207
  • Jorge Luis Rodas-Flores Servicio de Reumatología, Hospital Universitario Virgen Macarena, Sevilla, España https://orcid.org/0009-0001-7912-6532
  • Eloy Rivas-Infante Servicio de Anatomía Patológica, Hospital Universitario Virgen Rocío, Sevilla, España
  • Eduardo Carmona-Nimo Servicio de Medicina Interna, Hospital Universitario Virgen Macarena, Sevilla, España
  • Lucía Fernández-Rendón Servicio de Medicina Interna, Hospital Universitario Virgen Macarena, Sevilla, España https://orcid.org/0009-0003-3683-930X

DOI:

https://doi.org/10.32818/reccmi.a10n1a12

Keywords:

overlap myositis, inflammatory myopathies, anti-Ku, anti-RNP, rituximab

Abstract

Overlap myositis is a clinically heterogeneous and poorly recognized subtype of idiopathic inflammatory myopathy. Its incidence is unknown, mainly due to the lack of determination of myositis-associated antibodies (MAA). We present the case of a Colombian 34-year-old woman with generalized myalgias, asthenia, anorexia, self-limited febrile peaks, dyspnea and dysphagia. After medical evaluation and complementary tests, a definitive diagnosis was reached with the positivity of anti-Ku and anti-RNP antibodies.

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References

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Published

2025-04-28

How to Cite

1.
Luque-Linero P, Rodas-Flores JL, Rivas-Infante E, Carmona-Nimo E, Fernández-Rendón L. Overlap myositis, a diagnostic challenge where antibody determination enabled diagnostic confirmation. Rev Esp Casos Clin Med Intern [Internet]. 2025 Apr. 28 [cited 2025 Apr. 30];10(1):39-42. Available from: https://www.reccmi.com/RECCMI/article/view/1072