Hyponatremia due to SIADH secondary to subarachnoid and intraparenchymal hemorrhage: role of urea in treatment

Authors

  • Leonor Acha-Isasi Internal Medicine Department, Cruces University Hospital, Barakaldo, Bizkaia, Spain https://orcid.org/0009-0005-4798-4128
  • Carlota Gómez-Carballo Internal Medicine Department, Cruces University Hospital, Barakaldo, Bizkaia, Spain https://orcid.org/0000-0003-4860-0390
  • Ziortza Goiria-Elorduy Internal Medicine Department, Cruces University Hospital, Barakaldo, Bizkaia, Spain
  • Mario Villarreal-López de Muniain Internal Medicine Department, Cruces University Hospital, Barakaldo, Bizkaia, Spain
  • Agustín Martínez-Berriotxoa Internal Medicine Department, Cruces University Hospital, Barakaldo, Bizkaia, Spain

DOI:

https://doi.org/10.32818/reccmi.a9s1a7

Keywords:

hyponatremia, intracranial hemorrhages, syndrome of inappropriate ADH secretion, oral urea

Abstract

Urea has demonstrated to be an effective tool to treat hyponatremia caused by syndrome of inappropriate antidiuretic hormone secretion (SIADH) when the cause is not initially reversible. We present the case of a patient who, after suffering a traumatic brain injury with intracranial hemorrhagic complications, began to experience confusion caused by hyponatremia secondary to SIADH. Due to the lack of response to fluid restriction we initiated treatment with urea, with an improvement of the symptoms and the natremia. After the urea was discontinued the clinical picture returned, so the treatment was reintroduced and the dosage was slowly decreased until removal.

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References

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Published

2024-11-30

How to Cite

1.
Acha-Isasi L, Gómez-Carballo C, Goiria-Elorduy Z, Villarreal-López de Muniain M, Martínez-Berriotxoa A. Hyponatremia due to SIADH secondary to subarachnoid and intraparenchymal hemorrhage: role of urea in treatment. Rev Esp Casos Clin Med Intern [Internet]. 2024 Nov. 30 [cited 2024 Dec. 5];9(Supl. 1):17-9. Available from: https://www.reccmi.com/RECCMI/article/view/1059