Cardiac involvement in seronegative immune-mediated necrotizing myopathy

Authors

DOI:

https://doi.org/10.32818/reccmi.a9n2a19

Keywords:

inflammatory myopathy, necrotizing myopathy, extramuscular myopathy, myocarditis

Abstract

We present the case of a 43-year-old patient with weakness in the lower limbs that had been going on for
months, associated with dysphagia and severe weight loss, with elevated serum creatine kinase and an electrophysiological study compatible with inflammatory myopathy, with a pathological diagnosis of immune-mediated necrotizing myopathy (IMNM). After starting treatment, the patient presented symptoms of acute heart
failure after entering atrial fibrillation, showing biventrivular dysfunction and data of myocardial infiltration on cardioMRI.

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References

Pinal-Fernandez I, Casal-Dominguez M, Mammen AL. Immune-mediated necrotizing myopathy. Curr Rheumatol Rep. 2018; 20(4): 21. doi: https://doi. org/10.1007/s11926-018-0732-6 (último acceso jul. 2024). DOI: https://doi.org/10.1007/s11926-018-0732-6

Liu M, Lin Y, Qiao L, Chen J, Shi Q. Corrigendum: Characteristics of cardiac involvement in immune-mediated necrotizing myopathy. Front Immunol. 2023; 14: 1233453. doi: https://doi.org/10.3389/fimmu.2023.1233453 (últi¬mo acceso jul. 2024). DOI: https://doi.org/10.3389/fimmu.2023.1233453

Goyal NA. Immune-mediated myopathies. Continuum (Minneap Minn). 2019; 5(6): 1564-1585. doi: https://doi.org/10.1212/CON.0000000000000789 (último acceso jul. 2024). DOI: https://doi.org/10.1212/CON.0000000000000789

Allenbach Y, Benveniste O. Peculiar clinicopathological features of immune-mediated necrotizing myopathies. Curr Opin Rheumatol. 2018; 30(6): 655- 663. doi: https://doi.org/10.1097/BOR.0000000000000547 (último acceso jul. 2024). DOI: https://doi.org/10.1097/BOR.0000000000000547

Watanabe Y, Uruha A, Suzuki S, Nakahara J, Hamanaka K, Takayama K, Suzuki N, Nishino I. Clinical features and prognosis in anti-SRP and an¬ti-HMGCR necrotising myopathy. J Neurol Neurosurg Psychiatry. 2016; 87(10): 1038-1044. doi: https://doi.org/10.1136/jnnp-2016-313166 (últi¬mo acceso jul. 2024). DOI: https://doi.org/10.1136/jnnp-2016-313166

Zhang L, Zhu H, Yang P, Duan X, Wei W, Wu Z, et al. Chinese rheumatism data center-myositis registry (CRDC-MYO). Myocardial involvement in idiopathic inflammatory myopathies: a multi-center cross-sectional study in the CR¬DC-MYO Registry. Clin Rheumatol. 2021; 40(11): 4597-4608. doi: https://doi. org/10.1007/s10067-021-05828-y (último acceso jul. 2024). DOI: https://doi.org/10.1007/s10067-021-05828-y

Tamura T, Miyajima K,Watanabe K, Ito K, Kin F, Okazaki A, et al. An autop¬sy case of antibody-negative immune-mediated necrotizing myopathy with severe cardiac involvement. Intern Med. 2021. 60(19): 3113-3119. doi: https://doi.org/10.2169/internalmedicine.6355-20 (último acceso ago. 2024). DOI: https://doi.org/10.2169/internalmedicine.6355-20

Tsang D, Malladi CL, Patel K, Bajaj P. Seronegative immune-mediated ne¬crotising myopathy complicated by fulminant myocarditis resulting in car¬diogenic shock and cardiac arrest. BMJ Case Rep. 2022; 15(4): e248535. doi: https://doi.org/10.1136/bcr-2021-248535 (último acceso jul. 2024). DOI: https://doi.org/10.1136/bcr-2021-248535

Published

2024-08-26

How to Cite

1.
de Urrutia-Undabarrena I, Romero-Marín G, Josefa Andrea. Cardiac involvement in seronegative immune-mediated necrotizing myopathy. Rev Esp Casos Clin Med Intern [Internet]. 2024 Aug. 26 [cited 2024 Sep. 1];9(2):100-2. Available from: https://www.reccmi.com/RECCMI/article/view/1037