Apalutamide and interstitial lung disease, an association to take into account
DOI:
https://doi.org/10.32818/reccmi.a9n1a2Keywords:
interstitial lung disease, prostate cancer, apalutamide, antiandrogenic receptorAbstract
Interstitial lung disease (ILD) is a heterogeneous group of lung conditions whose etiology is varied, although toxins or other drugs can frequently cause it. Apalutamide is a selective inhibitor of androgen receptors used in cases of prostate cancer resistant to treatment with hormone blockade. There are three cases of drug-associated ILD published to date. We present a patient under treatment with apalutamide who developed a very rapid progression of ILD. An etiological diagnosis was made and treatment with high doses of corticosteroids was established, however, the patient died.
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Copyright (c) 2024 Manuel Raya-Cruz, Rocío Córdoba-Peinado, José Juan Moreno-Sánchez, José Luis Fernández-Reyes, Francisco Gómez-Delgado
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