A spontaneous bleeding of uncertain origin
DOI:
https://doi.org/10.32818/reccmi.a5n2a7Keywords:
hemophilia A, factor VIII, hemorrhagic disorders, autoantibodies.Abstract
Acquired hemophilia A is a rare disease caused by autoantibodies targeting coagulation factor VIII. It should be suspected in case of spontaneous bleeding and extended aPTT. We present an 85-year-old male patient with retroperitoneal hematoma and prolonged aPTT. Factor VIII activity is determined, which is significantly reduced. The patient begins treatment, with excellent clinical response. This is an illustrative
example of this unknown disease, which may provide its better understanding and management of these patients.
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Copyright (c) 2020 Ana Elvira-Laffond, David González-Calle, Miguel Hernández-Hidalgo, Ángel Víctor Hernández-Martos, María Sánchez Ledesma
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