Familial SIADH hyponatremia? Not everything is as it seems

Authors

  • Quico Fernández-Granero Internal Medicine Department, Jiménez Díaz Foundation University Hospital, Madrid, Spain https://orcid.org/0009-0001-2664-4627
  • Lucía Bañares-Díaz de Guereñu Internal Medicine Department, Jiménez Díaz Foundation University Hospital, Madrid, Spain https://orcid.org/0009-0002-8478-1934
  • Marta López-de las Heras Internal Medicine Department, Jiménez Díaz Foundation University Hospital, Madrid, Spain https://orcid.org/0009-0000-4094-3060

DOI:

https://doi.org/10.32818/reccmi.a9s1a11

Keywords:

hyponatremia, syndrome of inappropriate antidiuretic hormone secretion (SIADH), urea, spinal fractures, differential diagnosis

Abstract

Hyponatremia is a common but complex ionic disorder to be managed which requires an etiological diagnosis to ensure an effective solution and prevent a recurrence. On this clinical report we present a case of severe symptomatic hyponatremia, emphasizing the importance of a meticulous differential diagnosis (considering a hereditary origin’s suspicion). This approach allows an etiology-oriented management aiming to solve the main problem and, as a result, the ionic effects.

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References

Luzecky MH, Burman KD, Schultz ER. The syndrome of inappropriate secretion of antidiuretic hormone associated with amitriptyline administration. South Med J. 1974; 67(4): 495-497. doi: https://doi.org/10.1097/00007611-197404000-00027 (último acceso sept. 2024). DOI: https://doi.org/10.1097/00007611-197404000-00027

Pinkhasov A, Xiong G, Bourgeois JA, Heinrich TW, Huang H, Coriolan S, et al. Management of SIADH-related hyponatremia due to psychotropic medications - an expert consensus from the Association of Medicine and Psychiatry. J Psychosom Res. 2021; 151: 110654. doi: https://doi.org/10.1016/j.jpsychores.2021.110654 (último acceso sept. 2024). DOI: https://doi.org/10.1016/j.jpsychores.2021.110654

Varsavsky M, Quesada Charneco M, Rozas Moreno P. Urea como opción terapéutica para el tratamiento del síndrome de secreción inadecuada de hormona antidiurética (SIADH). Med Clin (Barc). 2011; 137(5): 237-238. doi: https://doi.org/10.1016/j.medcli.2010 .09.023 (último acceso sept. 2024). DOI: https://doi.org/10.1016/j.medcli.2010.09.023

Warren AM, Grossmann M, Christ-Crain M, Russell N. Syndrome of inappropriate antidiuresis: from pathophysiology to management. Endocr Rev. 2023; 44(5): 819-861. doi: https://doi.org/10.1210/endrev/bnad010 (último acceso sept. 2024). DOI: https://doi.org/10.1210/endrev/bnad010

Published

2024-11-30

How to Cite

1.
Fernández-Granero Q, Bañares-Díaz de Guereñu L, López-de las Heras M. Familial SIADH hyponatremia? Not everything is as it seems. Rev Esp Casos Clin Med Intern [Internet]. 2024 Nov. 30 [cited 2024 Dec. 26];9(Supl. 1):29-31. Available from: https://www.reccmi.com/RECCMI/article/view/1063